Qing Wang

Androgen depletion increases sensitivity to effort-related costs and alters mesoaccumbal circuit function in male mice

This study shows that androgen depletion in male mice increases sensitivity to effort costs and alters mesoaccumbal circuit function, with distinct effects depending on the timing of hormone loss.

MVCBench: A Multimodal Benchmark for Drug-induced Virtual Cell Phenotypes

MVCBench evaluates drug molecular and gene representation methods for predicting drug-induced multimodal cell phenotypes using transcriptomic and imaging data.

Cell Type-Specific Changes in Dendritic Spines Across Adolescence Within Mouse Medial Prefrontal Cortex

The paper examines dendritic spine changes in mouse medial prefrontal cortex neurons during adolescence, finding greater remodeling in IT-type neurons and a role for microglia.

Associations between COVID-19 and putative markers of neuroinflammation: A diffusion basis spectrum imaging study.

This study investigates associations between COVID-19 and neuroinflammation markers using DBSI in UK Biobank data, finding increased vasogenic edema in specific brain regions.

Core Transcription Programs Controlling Injury-Induced Neurodegeneration of Retinal Ganglion Cells

The paper identifies four ATF/CEBP transcription factors that drive injury-induced neurodegeneration of retinal ganglion cells and shows their role in glaucoma.

CRISPR-Cas9 targeted deletion of the C9orf72 repeat expansion mutation corrects cellular phenotypes in patient-derived iPS cells

CRISPR-Cas9 removes the C9orf72 repeat expansion in iPS cells, reducing RNA foci and promoter hypermethylation without affecting C9orf72 expression.

RNA-seq: primary cells, cell lines and heat stress

The paper uses RNA-seq to analyze gene expression in chicken and human cells under heat stress conditions to identify differentially expressed genes.