Author

Johanna Olweus

Oslo University HospitalORCID 0000-0002-1898-3100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Anna Zofia KomisarczukiD· 1 shared Antti TuhkalaiD· 1 shared Britt Olaug Lindestad· 1 shared Camilla Schalin‐JänttiiD· 1 shared Carolina Wieczorek ErvikiD· 1 shared Christoph ZiegenhainiD· 1 shared Eero Tölö· 1 shared Eira LeinoneniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

Anna Zofia KomisarczukORCID

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2 papers

Recent·Most cited

Immediate transcriptional changes initiated by direct cell-cell contact between cytotoxic T cells and cancer cells

Zhouhui Qi, Madeleine Lehander, Narmadha Subramanian, Eirini Giannakopoulou, Johanna Olweus, Michael Hagemann-Jensen, Christoph Ziegenhain, Petter S. Woll

The paper investigates immediate transcriptional changes in T cells upon direct contact with cancer cells using single-cell transcriptomics and identifies distinct T cell subsets associated with reduced TCR diversity.

bioRxiv · Feb 18, 2026 · PreprintImmunology

T cell correction pipeline for Inborn Errors of Immunity

Katariina Mamia, Sólrún Kolbeinsdóttir, Kornel Labun, Zhuokun Li, Anna Zofia Komisarczuk, Salla Keskitalo, Ganna Reint, Frida Loe Haugen, Britt Olaug Lindestad, Siv Skundberg Jensen, Thea Johanne Gjerdingen, Antti Tuhkala, Carolina Wieczorek Ervik, Pavel Kopcil, Nail Fatkhutdinov, , Emma Maria Haapaniemi

This paper presents a T cell gene correction pipeline using CRISPR/Cas9 and HDR to correct monogenic mutations in IEI models, achieving up to 80% bi-allelic editing with no detectable off-target effects.

Molecular Therapy · Aug 12, 2025Peer-reviewedBioengineering