Author

Lucy J. Davison

Royal Veterinary CollegeORCID 0000-0002-1920-0817Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:fine-mapping· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Christopher A. O’CallaghaniD· 2 shared Thomas K. HironiD· 2 shared Anja KipariD· 1 shared Benjamin DaviesiD· 1 shared CA O’ Callaghan· 1 shared Christopher Preece· 1 shared Edward DrydaleiD· 1 shared Emi BarkeriD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

Christopher A. O’CallaghanORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Fatal consequences of feline coronavirus infection are associated with virus persistence and a distinct adaptive immune repertoire

Thomas K. Hiron, Sara Falcone, Anja Kipar, Melanie Hezzell, Christopher A. O’Callaghan, Emi Barker, Lucy J. Davison

This study identifies immune repertoire changes and viral evolution in feline coronavirus infection, linking them to FIP severity and outcomes.

bioRxiv · Oct 2, 2025 · PreprintImmunology

Partitioning heritability using single-cell multi-omics identifies a novel macrophage subpopulation conveying genetic risks of coronary artery disease.

Jiahao Jiang, Thomas K. Hiron, Thomas A. Agbaedeng, Yashaswat Malhotra, Edward Drydale, James M. Bancroft, Esther Ng, Michael E. Reschen, Lucy J. Davison, Christopher A. O’Callaghan

The paper identifies a novel macrophage subpopulation, lipid-handling macrophages, that is enriched with CAD genetic risk and shows how a risk variant affects FDX1 through AP-1 and C/EBP-beta recruitment.

bioRxiv · Sep 14, 2023 · PreprintGenetics

Dexi disruption depletes gut microbial metabolites and accelerates autoimmune diabetes

LJ Davison, Marsha D. Wallace, Christopher Preece, Katherine Hughes, John A. Todd, Benjamin Davies, CA O’ Callaghan

Disruption of the Dexi gene accelerates diabetes in NOD mice and alters serum immunoglobulins, gut microbiome, and microbial metabolites.

bioRxiv · Aug 16, 2018 · PreprintGenetics