Cancer BiologyNature CommunicationsPeer-reviewed
Identifying phenotype-genotype-function coupling in 3D organoid imaging using Shape, Appearance and Motion Phenotype Observation Tool (SPOT)
Felix Zhou, Brittany‐Amber Jacobs, Adam Norton-Steele…·Xin Lü
The paper develops SPOT, a tool for analyzing 3D morpho-dynamics from 2D live-cell imaging, and applies it to organoids to identify phenotype-genotype-function relationships.