Author

Carl Lee

University of OxfordORCID 0000-0002-6776-2793Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Physiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Alex Nicolas Gordon-WeeksiD· 2 shared Michael Loran DustiniD· 2 shared Rachael J. M. Bashford-RogersiD· 2 shared Shihong WuiD· 2 shared Adam Frampton· 1 shared Adil Siraj LakhaiD· 1 shared Ahmet HaziniiD· 1 shared Alessandro CiccarelliiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Alex Nicolas Gordon-WeeksORCID

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Author profile →

4 papers

Recent·Most cited

Engineered HMGB1 construct with tandem Box B domains promotes tissue regeneration without potential for deleterious inflammation or thrombosis

Alvaro Viñals Guitart, Carl Lee, Ana Isabel Espirito Santo, Jia-Ling Ruan, Shih-Hsuan Mao, Lynn William, Christina Redfield, Oleg Fedorov, N. Burgess-Brown, Wyatt W. Yue, Jagdeep Nanchahal

iScience · Aug 1, 2026Peer-reviewedBiochemistry

Machine perfusion and single-cell spatial transcriptome mapping identifies novel immune escape mechanisms in colorectal cancer liver metastasis

Peter Kok-Ting Wan, Ranchu Cheng, David Johnson, Carl Lee, Shihong Wu, Areeb Mian, Ahmet Hazini, Sorayya Moradi, Kenneth Friesen, Flurin Caviezel, Syed Hussain Abbas, Hatem Sadik, Adil Siraj Lakha, Keaton Ian Jones, Girishkumar Kaitholil Kumaran, , Alex Nicolas Gordon-Weeks

bioRxiv · Dec 11, 2025 · PreprintCancer Biology

SpatioEv: Spatial evolution of protein and morphological features reveals development dynamics of cells and spatial neighbourhoods

Shihong Wu, Sakina Amin, Carl Lee, Jean-Baptiste Richard, Nabeel Merali, Caroline Morrell, Lauren Overend, Wei Gao, Felicia Tucci, Alex Nicolas Gordon-Weeks, Adam Frampton, Nicola E. Annels, Emma Louise Culver, Michael Loran Dustin, Kim S. Midwood, Rachael J. M. Bashford-Rogers

SpatioEv analyzes spatial data to reveal cell and neighborhood dynamics, identifying disease-specific spatial signatures and developmental trajectories in tissues.

bioRxiv · Jun 30, 2025 · PreprintSystems Biology

Sympathetic neuron-derived NPY protects from obesity by sustaining the mural progenitors of thermogenic adipocytes.

Yitao Zhu, Lu Yao, Ana Luisa Gallo-Ferraz, Bruna Bombassaro, Marcela Reymond Simoes, Ichitaro Abe, Jing Wen Chen, Gitalee Sarker, Alessandro Ciccarelli, Linna Zhou, Carl Lee, Davi Sidarta-Oliveira, Noelia Martínez‐Sánchez, Michael Loran Dustin, Cheng Zhan, , Ana Isabel Domingos

This study shows that sympathetic neuron-derived NPY sustains mural progenitors of thermogenic adipocytes, protecting against obesity by maintaining thermogenic capacity.

Nature · Aug 28, 2024Peer-reviewedPhysiology