The Drosophila chemokine-like Orion bridges phosphatidylserine and Draper in phagocytosis of neurons
Hui Ji, Bei Wang, Yifan Shen, David Labib, Joyce Lei, Xinchen Chen, Maria L. Sapar, Ana Boulanger, Jean‐Maurice Dura, Chun Han
This study identifies Orion as a bridging molecule that connects phosphatidylserine and Draper in Drosophila phagocytosis of degenerating neurons, revealing a conserved mechanism.
Proceedings of the National Academy of Sciences · Jun 5, 2023Peer-reviewedNeuroscience