Author

Jason M. Spaeth

Indiana University IndianapolisORCID 0000-0002-1945-4323Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Abigail TwoyiD· 1 shared Anup R. SharmaiD· 1 shared CATE SPEAKEiD· 1 shared Emily Soohoo· 1 shared Everett H. MeyeriD· 1 shared Farooq SyediD· 1 shared Jon D. PiganelliiD· 1 shared Jyoti RanaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Abigail TwoyORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintApr 2, 2026

Soluble LAG-3 Identifies a Dynamic Early T Cell Activation Window in self-reactivity, Type 1 Diabetes, and Broader Immune Responses.

Saptarshi Roy, Megan Lynn Proffer, Farooq Syed…·Jon D. Piganelli

This study identifies soluble LAG-3 (sLAG-3) as an early biomarker of T cell activation in type 1 diabetes, detectable before islet autoantibody development and associated with beta-cell stress and high-risk HLA genotypes.

1 citation

mousehuman

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