Xiuqing Zhang

IntroSpect improves HLA binding peptide identification sensitivity by 80% using motif-guided database building, while maintaining high accuracy and FDR control.

BDdb is a database integrating multi-omics data, cfDNA data, and biomarkers for birth defects, enabling data exploration and analysis for research and clinical applications.

This study identifies recurrent neoantigens in breast cancer by analyzing somatic mutations and their immunogenic potential through HLA recognition.

The paper identifies hundreds of genes deregulated by SVs in cancer, showing increased expression linked to SV breakpoints and enhancer elements.

The paper identifies two molecular subtypes of lung adenocarcinomas based on tumor mutation burden and links them to clinical and genomic differences.

This study analyzes molecular profiles and mutation burden in Chinese gastric carcinoma patients, identifying gene alterations and genomic regions linked to tumor burden and prognosis.

This study identifies novel somatic mutations and altered mutation frequencies in Chinese colorectal cancer patients using whole exome sequencing, highlighting differences from TCGA data.