Author

Leland L. Metheny

University Hospitals of ClevelandORCID 0000-0002-1980-9999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Claire E. FritziD· 1 shared David N. WaldiD· 1 shared Paolo Fabrizio CaimiiD· 1 shared Reshmi ParameswaraniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Claire E. FritzORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintNov 22, 2025

B-cell activating factor plays a critical role in CAR-T cell-associated cytokine release syndrome

Claire E. Fritz, Leland L. Metheny, David N. Wald…·Reshmi Parameswaran

This study identifies BAFF as a key mediator of CAR-T cell-related cytokine release syndrome and shows that neutralizing BAFF reduces cytokine production without affecting CAR-T cell function.

DOI 10.1101/2025.11.22.689920

humanproteomics

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