Author

Matteo Giovanni Della Porta

IRCCS Humanitas Research HospitalORCID 0000-0002-1984-1614Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

Francesca FicaraiD· 1 shared Francis BaumgartneriD· 1 shared Gabriele TodiscoiD· 1 shared Manoj M. PillaiiD· 1 shared Prajwal Chaitanya BodduiD· 1 shared Rahul Roy· 1 shared Stephan HütteriD· 1 shared Torsten HaferlachiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Francesca FicaraORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintOct 8, 2025

A Unifying Mechanism for Shared Splicing Aberrations in Splicing Factor Mutant Cancers

Prajwal Chaitanya Boddu, Rahul Roy, Stephan Hütter…·Manoj M. Pillai

This study identifies a shared trans-acting mechanism in splicing factor mutant cancers that drives retained intron (RI) splicing defects through DDR-induced AMPK-AKT imbalance and SRSF1 hypophosphorylation.

DOI 10.1101/2025.10.08.679601

humanbulk RNA-seq

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