Author

Stephan Hütter

Munich Leukemia Laboratory (Germany)ORCID 0000-0003-2432-8898Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Torsten HaferlachiD· 2 shared Alina HartmanniD· 1 shared Anjali CremeriD· 1 shared Björn-Thore HanseniD· 1 shared Claudia Dorothea BaldusiD· 1 shared Claudia HaferlachiD· 1 shared Dong‐Er ZhangiD· 1 shared Francesca FicaraiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

Torsten HaferlachORCID

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3 papers

Recent·Most cited

Cancer BiologyHemaSpherePeer-reviewedApr 1, 2026

IntegrateALL: an end-to-end RNA-seq analysis pipeline for multilevel data extraction and interpretable subtype classification in B-precursor ALL

Nadine Wolgast, Thomas Beder, Mayukh Mondal…·Lorenz Bastian

IntegrateALL is an RNA-seq pipeline that integrates expression-based subtyping, gene fusion detection, and virtual karyotyping to classify B-ALL with high accuracy.

1 citation

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintOct 8, 2025

A Unifying Mechanism for Shared Splicing Aberrations in Splicing Factor Mutant Cancers

Prajwal Chaitanya Boddu, Rahul Roy, Stephan Hütter…·Manoj M. Pillai

This study identifies a shared trans-acting mechanism in splicing factor mutant cancers that drives retained intron (RI) splicing defects through DDR-induced AMPK-AKT imbalance and SRSF1 hypophosphorylation.

DOI 10.1101/2025.10.08.679601

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintAug 3, 2023

Interface-guided phenotyping of coding variants in the transcription factor RUNX1 with SEUSS

Kıvılcım Öztürk, Rebecca Panwala, Jeanna Sheen…·Hannah K. Carter

The paper uses SEUSS to analyze the effects of 115 RUNX1 mutations on RNA profiles in myelogenous leukemia cells, categorizing them into three functional groups.

DOI 10.1101/2023.08.03.551876

humanbulk RNA-seq

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