Lidia Yshii

The paper investigates immune dysfunction in cirrhosis by analyzing CD8ab⁺ intraepithelial lymphocytes and identifies CCL25-CCR9 axis disruption as a key factor.

This study demonstrates that CRISPR-CasRx reduces C9orf72 repeat RNAs and DPRs in vitro and in vivo, suggesting its therapeutic potential for ALS/FTD.

This study shows that topical antibiotics reduce skin bacteria in mice, leading to faster Zika virus disease progression and higher viral loads in multiple tissues.

This study shows that delivering IL2 to the brain in aging mice partially restores molecular signatures of aging and improves spatial learning.