Leen Delang

This study evaluates antiviral sugar baits (AVSBs) in mosquitoes to block dengue and chikungunya virus transmission, finding that 4'FlU and JNJ-A07 reduce viral infection and dissemination.

The paper analyzes microbial diversity in Aedes aegypti mosquitoes across life stages and breeding sites, finding convergent enrichment of Gammaproteobacteria, suggesting maternal transmission.

This study shows that inhibiting Hsp70 reduces chikungunya virus infectious particle production without harming host cells.

This study assesses the vector competence of European mosquitoes for Oropouche virus strains and finds low transmission risk.

Flavitransin inhibits dengue virus polyprotein insertion into the ER membrane, showing broad antiviral activity against flaviviruses.

This study evaluates combinations of approved oral nucleoside analogues against multiple alphaviruses in vitro and in vivo, finding synergistic antiviral effects and reduced viral mutation rates with combination therapy.

This study identifies CCR2 as critical for monocyte recruitment and BBB disruption in USUV encephalitis, showing therapeutic benefit from glucocorticoid treatment.

This study shows that topical antibiotics reduce skin bacteria in mice, leading to faster Zika virus disease progression and higher viral loads in multiple tissues.

The paper reports the first detection of kdr L1014F and ace-1 G119S insecticide resistance mutations in Belgian Culex mosquitoes, highlighting the need for surveillance.

This paper demonstrates that ex vivo midgut cultures of Aedes aegypti mosquitoes can be efficiently infected by mosquito-borne alpha- and flaviviruses and used to test antiviral compounds.

This study shows that FTO affects m6A marking on SARS-CoV-2 RNA and correlates with COVID-19 severity in patients.

The paper describes the development of a broadly neutralizing antibody, XVR011, effective against SARS-CoV-2 and its variants in animal models.