Chao Peng

This study identifies six pesticides linked to increased Parkinson's disease risk through three screens and in vivo testing in zebrafish.

This paper investigates the association between chlorpyrifos exposure and Parkinson's disease risk, finding increased odds of PD with long-term exposure and demonstrating causal mechanisms in animal models.

This study shows that α-synuclein pathology in mice visual cortex reduces neuronal activity in affected cells and alters population activity but does not impair visuoperceptual function.

The paper identifies presynaptic and postsynaptic risk genes and key connectomes involved in pathological α-synuclein spreading using mathematical models and gene regulatory network analysis.

This study investigates how acetylation of specific lysine sites in α-synuclein affects aggregation and function, identifying K80 acetylation as a potential therapeutic target.

SCING improves GRN inference accuracy and interpretability using gradient boosting and mutual information on scRNAseq, snRNAseq, and spatial transcriptomics data.