Genetic Code Expansion and Enzymatic Modifications as Accessible Methods for Studying Site-Specific Post-Translational Modifications of Alpha-Synuclein and Tau
Ibrahim G. Saleh, Marie Shimogawa, Jennifer Ramirez, Bernard Abakah, Yarra Venkatesh, Honey Priya James, Minghao Li, Sarah A. Louie, Marshall G. Lougee, Wai‐Kit Chia, Christopher R. Brue, Richard B. Cooley, Ryan A. Mehl, Tobias Baumgart, Robert H. Mach, , E. James Petersson
The paper provides methods for site-specific post-translational modification of alpha-synuclein and tau using genetic code expansion and enzymatic approaches, enabling studies of their structural dynamics and aggregation.
Protein Science · Sep 13, 2025Peer-reviewedBiochemistry