Author

Xianrong Wong

Johns Hopkins UniversityORCID 0000-0002-1995-7043Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Assay:Hi-C· 2 Research Focus:spatial domain detection· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Karen L. ReddyiD· 4 shared James TayloriD· 2 shared Katja PekruniD· 2 shared Akhilesh PandeyiD· 1 shared Anil Kumar MadugunduiD· 1 shared Cheng‐Ming ChuongiD· 1 shared Emily A. DeBoyiD· 1 shared Hunter W. RichardsiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersGenomics

Karen L. ReddyORCID

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4 papers

Recent·Most cited

Genome organization by SATB1 binding to base-unpairing regions (BURs) provides scaffold for SATB1-regulated gene expression

Yoshinori Kohwi, Xianrong Wong, Mari Grange, Tom Sexton, Hunter W. Richards, Yohko Kitagawa, Shimon Sakaguchi, Ya‐Chen Liang, Cheng‐Ming Chuong, Vladimir A. Botchkarev, Ichiro Taniuchi, Karen L. Reddy, Terumi Kohwi-shigematsu

The paper identifies SATB1's role in genome organization through direct binding to BURs, linking chromatin structure to cell type-specific gene expression.

eLife · Oct 2, 2025Peer-reviewedGenomics

Mapping the micro-proteome of the nuclear lamina and lamin associated domains

Jevon A. Cutler, Xianrong Wong, Victoria E. Hoskins, Molly R. Gordon, Anil Kumar Madugundu, Akhilesh Pandey, Karen L. Reddy

The paper identifies proteins associated with the nuclear lamina and lamin associated domains using BioID and m6A-tracer systems, revealing key regulators of LAD function.

Life Science Alliance · Mar 23, 2021Peer-reviewedGenomics

The repressive genome compartment is established early in the cell cycle before forming the lamina associated domains

TR Luperchio, MEG Sauria, VE Hoskins, Xianrong Wong, Emily A. DeBoy, M-C Gaillard, Peter W. K. Tsang, Katja Pekrun, RA Ach, Nazumi Alice Yamada, James Taylor, Karen L. Reddy

The paper shows that the B-compartment self-organizes early in the cell cycle before associating with the nuclear lamina.

bioRxiv · Nov 29, 2018 · PreprintGenomics

Chromosome Conformation Paints Reveal The Role Of Lamina Association In Genome Organization And Regulation

Teresa R Luperchio, Michael EG Sauria, Xianrong Wong, Marie-Cécile Gaillard, Peter Tsang, Katja Pekrun, Robert A Ach, N Alice Yamada, James Taylor, Karen L Reddy

This study uses chromosome conformation paints to show that LADs form compact regions at the nuclear lamina and are linked to B compartments, with some regions interacting with the A compartment.

bioRxiv · Mar 30, 2017 · PreprintCell Biology