Author

Jian‐Sheng Lin

Lyon 1 UniversitéORCID 0000-0002-2004-6079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Drosophila· 2 Organism:mouse· 2 Assay:electronic health records· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Laurent SeugnetiD· 2 shared Anne Jouvet· 1 shared Aurore GuyoniD· 1 shared B. KugeneriD· 1 shared Céline Scoté-Blachon· 1 shared Christelle AnacletiD· 1 shared Claire Benetollo· 1 shared Clara Odilia Inocente· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersNeuroscience

Laurent SeugnetORCID

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4 papers

Recent·Most cited

A Quest for a Histaminergic or Orexinergic Biomarker for Sudden Infant Death Syndrome

Yan Zhao, Guang-Fu Cui, Sabine Plancoulaine, Marion Comajuan, Marine Bersault, Clara Odilia Inocente, Yiping Hou, Yves A Dauvilliers, Manuela Lotierzo, Aurore Guyon, David Meyronet, Anne Jouvet, B. Kugener, Marine Thieux, Philippe Robert, , Patricia Franco

This study examines the role of histaminergic and orexinergic systems in SIDS by analyzing CSF levels and neuronal counts, finding increased orexin activity but no significant HA differences.

Pediatric Research · Jun 22, 2026Peer-reviewedNeuroscience

The acute sleep-inducing effects of light require histamine neurotransmission in mice

Yanlong Hou, Ni Tang, Sophie Wu, Yu-Feng Shao, Jian‐Sheng Lin, Claude Gronfier

This study shows that light-induced sleep in mice requires histamine neurotransmission, as demonstrated by reduced sleep responses in HDC knockout and chemogenetically silenced mice.

bioRxiv · Jun 26, 2025 · PreprintNeuroscience

Pallidin function in drosophila surface glia regulates sleep and is dependent on amino acid availability

Hui Li, Sami Aboudhiaf, Sandrine Parrot, Céline Scoté-Blachon, Claire Benetollo, Jian‐Sheng Lin, Laurent Seugnet

This paper shows that reducing Pallidin in Drosophila surface glia disrupts sleep and that this effect depends on amino acid availability.

Cell Reports · Sep 1, 2023Peer-reviewedNeuroscience

A marked enhancement of a BLOC-1 gene, pallidin, associated with somnolent mouse models deficient in histamine transmission

Laurent Seugnet, Christelle Anaclet, Magali Perier, Jean‐François Ghersi‐Egea, Jian‐Sheng Lin

The paper identifies pallidin, a BLOC-1 gene, as upregulated in mice lacking histamine and orexin, associated with sleep disorders and altered neurotransmitter systems.

CNS Neuroscience & Therapeutics · Oct 18, 2022Peer-reviewedNeuroscience