Structural insights into the mammalian late-stage initiation complexes
Angelita Simonetti, Ewelina Guca, Anthony Bochler, Lauriane Kühn, Yaser Hashem
The paper presents cryo-EM structures of mammalian late-stage 48S initiation complexes with different mRNA sequences, revealing mRNA-eIF interactions and the structural role of ABCE1.
Cell Reports · Apr 1, 2020Peer-reviewedMolecular Biology