Author

Yvonne Y.C. Yeap

Agency for Science, Technology and ResearchORCID 0000-0002-2015-0685Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Dominic C.H. NgiD· 2 shared Cheng Hui Goh· 1 shared Chi CheniD· 1 shared Julia K. PaganiD· 1 shared Matthew J. MorrisiD· 1 shared Peter G. NoakesiD· 1 shared S. Sean MillardiD· 1 shared Uda Y. HoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

Dominic C.H. NgORCID

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2 papers

Recent·Most cited

WDR62 and CEP170 recruit MAPKBP1 for pericentriolar material cohesion and mitotic spindle formation.

Uda Y. Ho, Yvonne Y.C. Yeap, Cheng Hui Goh, Peter G. Noakes, Dominic C.H. Ng

This study identifies MAPKBP1 as a centrosomal protein that forms a complex with WDR62 and CEP170, essential for PCM cohesion and mitotic spindle formation.

bioRxiv · Feb 24, 2026 · PreprintCell Biology

The microcephaly protein WDR62 regulates cellular purine metabolism through the HSP70/HSP90 chaperone machinery.

Matthew J. Morris, Yvonne Y.C. Yeap, Chi Chen, S. Sean Millard, Julia K. Pagan, Dominic C.H. Ng

This study identifies WDR62's role in regulating purine metabolism via the HSP70/HSP90 chaperone network, linking its dysfunction to microcephaly through metabolic enzyme instability.

bioRxiv · Jul 1, 2024 · PreprintCell Biology