Cell BiologybioRxivPreprint
The microcephaly protein WDR62 regulates cellular purine metabolism through the HSP70/HSP90 chaperone machinery.
Matthew J. Morris, Yvonne Y.C. Yeap, Chi Chen…·Dominic C.H. Ng
This study identifies WDR62's role in regulating purine metabolism via the HSP70/HSP90 chaperone network, linking its dysfunction to microcephaly through metabolic enzyme instability.
3 citations