Molecular BiologybioRxivPreprint
Methylome profiling of SetDB1 deficient ESCs reveals diverse epigenetic cross-talk during pluripotency
Nick G.P. Bovee, Stefan H. A. Hoogland, Ehsan Habibi…·Hendrik Marks
This study investigates DNA methylation changes in SetDB1-deficient mouse ESCs, revealing its role in silencing retrotransposons and imprinted regions through coordination with H3K9me3.
DOI 10.1101/2025.06.18.660343