BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewed
Revisiting the need for mRNA nucleoside modification in CAR T cell engineering
Nourhan Kahwaji, Niklas Kotzian, Jasmin Melissa Prinz…·Norman Michael Drzeniek
This study shows that unmodified mRNA can be used for CAR-T cell engineering without compromising function, eliminating the need for costly nucleoside modifications.
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