Author

Charlotte Maeve Dunne

Berlin-Brandenburger Centrum für Regenerative TherapienORCID 0000-0002-4430-5717Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Ansgar Santel· 2 shared Daniel TonderaiD· 2 shared Katrin RadloffiD· 2 shared Leonidas Gkionis· 2 shared Manfred GosseniD· 2 shared Nourhan KahwajiiD· 2 shared Oliver KeiliD· 2 shared Akanksha MogaiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPharmacology & Toxicology

Ansgar Santel

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintSep 29, 2026

Translational Pharmacokinetics and Pharmacodynamics of a Cationic mRNA-Lipid Nanoparticle from Mice to Non-Human Primates

Charlotte Maeve Dunne, Katrin Radloff, Leonidas Gkionis…·Jorg Kaufmann

This study evaluates the pharmacokinetics and immunostimulatory effects of a cationic mRNA-LNP in non-human primates, identifying a biomarker for Tie2 signaling.

DOI 10.64898/2026.09.23.749423

non-human primatebulk RNA-seq

𝕏 PostBluesky

BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewedJan 5, 2026

Revisiting the need for mRNA nucleoside modification in CAR T cell engineering

Nourhan Kahwaji, Niklas Kotzian, Jasmin Melissa Prinz…·Norman Michael Drzeniek

This study shows that unmodified mRNA can be used for CAR-T cell engineering without compromising function, eliminating the need for costly nucleoside modifications.

7 citationstop 1%

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintOct 12, 2022

Spatial expression of an mRNA encoding Tie2-agonist in the capillary endothelium of the lung prevents pulmonary vascular leakage

Katrin Radloff, Birgitt Gutbier, Charlotte Maeve Dunne…·Martin Witzenrath

This study evaluates a synthetic mRNA encoding a hyperactive Ang1 fusion protein to prevent pulmonary vascular leakage in lung injury models.

DOI 10.1101/2022.10.12.511878

mouseexperimental assay

𝕏 PostBluesky