Li He

Human hippocampal ripples predict the alignment of experience to a grid-like schema

The paper shows that hippocampal ripples during rest predict the emergence of grid-like codes in the brain for inferring novel relationships in a 2D conceptual space.

ErbB inhibition impairs cognition via disrupting myelination and aerobic glycolysis in oligodendrocytes

This study shows that ErbB inhibition in oligodendrocytes disrupts myelination and aerobic glycolysis, impairing working memory in mice.

Sustained ErbB activation causes demyelination and hypomyelination by driving necroptosis of mature oligodendrocytes and apoptosis of oligodendrocyte precursor cells

ErbB dysregulation impairs cognition via myelination-dependent and -independent oligodendropathy

This study shows that ErbB dysregulation in oligodendrocytes causes white matter abnormalities in mice through myelination-dependent and -independent mechanisms, affecting cognition.