Kenji F. Tanaka

The paper identifies a stress-induced pain circuit involving locus coeruleus noradrenergic neurons and spinal astrocytes in mice, showing their role in mechanical pain hypersensitivity.

This study investigates how optogenetic manipulation of DRN serotonergic neurons affects motor actions and waiting behavior in mice during reward tasks, finding distinct effects on sustained actions versus stationary waiting.

The paper shows that different antidepressants induce similar structural and molecular changes in the pallidum of mice, suggesting a common mechanism in their antidepressant effects.

The paper shows optogenetic activation of dorsal raphe serotonin neurons in mice causes brain-wide activation, which is reduced under anesthesia.

The paper develops a reinforcement learning model to capture choice behavior during progressive ratio tasks, finding that the Perseverance model with choice traces best explains behavioral responses to drug effects.

This paper identifies shared GABA transmission pathology in L-DOPA-induced and tardive dyskinesia models through structural and functional analysis of striatal neurons.

This study shows that D2-MSNs in the lateral ventral striatum induce NREM sleep and coordinate with medial VS D2-MSNs in sleep regulation.

The paper demonstrates that optogenetic actuators in starburst amacrine cells enhance visual restoration in murine retinas through gap junctions.

The paper shows that larger reward expectations in mice are associated with slower dopamine rise and larger dopamine dip in the ventral striatum during task performance.

This paper classifies sleep stages in head-fixed mice using pupil dynamics and an LSTM model, achieving higher accuracy than a feed forward neural network.

This paper shows that dopamine responses shift backward in time during associative learning, aligning with TD prediction error models.

This study shows that population-level activity of dorsal raphe 5-HT neurons oscillates during NREM sleep, influencing EEG and EMG patterns, and suggests similar activity in humans.

This study shows that astrocyte Ca2+ levels change with sleep/wakefulness states and vary across brain regions in mice.

This paper introduces a flexible annotation atlas for the mouse brain that allows combining or dividing brain structures while maintaining anatomical hierarchy, improving ROI consistency across studies.

The paper characterizes astrocyte endfoot dimensions along the vascular tree in mice and shows that varying endfoot sizes maintain perivascular-interstitial fluid flux despite pressure changes.

This study shows that ErbB dysregulation in oligodendrocytes causes white matter abnormalities in mice through myelination-dependent and -independent mechanisms, affecting cognition.