Author

Sophie Hyesuk Lee

University of California, Santa CruzORCID 0000-0002-2049-9756Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1 Assay:multiome· 1

Frequent Co-Authors

Antonia HamrickiD· 1 shared Arcelia Gonzalez Jimenez· 1 shared Catherine Oh· 1 shared Guillermo Chacaltana· 1 shared H. Phong· 1 shared Hanzhang Tao· 1 shared Isabel Quesada· 1 shared Jeremy R. SanfordiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Antonia HamrickORCID

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1 paper

Recent·Most cited

Rescue of blood coagulation Factor VIII exon-16 mis-splicing by antisense oligonucleotides

Victor Tse, Guillermo Chacaltana, Martin E Gutierrez, Nicholas M. Forino, Arcelia Gonzalez Jimenez, Hanzhang Tao, H. Phong, Catherine Oh, Priyanka Chary, Isabel Quesada, Antonia Hamrick, Sophie Hyesuk Lee, Michael D. Stone, Jeremy R. Sanford

The paper identifies a three-way junction structure in intron 15 that affects F8 pre-mRNA splicing and shows that antisense oligonucleotides targeting this structure can rescue splicing defects in Hemophilia A.

bioRxiv · Mar 31, 2023 · PreprintMolecular Biology