Antonia Hamrick

The paper measures repair kinetics during C. elegans meiosis and finds similar rates for sister- and homolog-directed repair, challenging the assumption of homolog bias.

This study shows that sister chromatids are resolved early in C. elegans meiosis, and that cohesin activity is required for this resolution, which enables homolog bias in recombination.

The paper identifies a three-way junction structure in intron 15 that affects F8 pre-mRNA splicing and shows that antisense oligonucleotides targeting this structure can rescue splicing defects in Hemophilia A.