Author

Zia Fatma

University of Illinois Urbana-Champaign

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:CRISPR screen· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1 Organism:non-human primate· 1

Frequent Co-Authors

Huimin ZhaoiD· 4 shared Joshua D. RabinowitziD· 2 shared Shih‐I TaniD· 2 shared Vinh Gia TraniD· 2 shared Yasuo YoshikuniiD· 2 shared Yihui SheniD· 2 shared Aashutosh Girish BoobiD· 1 shared Andrei Stecca SteindorffiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersSynthetic Biology

Huimin ZhaoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MAESTRO uncovers tandem paralog dynamics as a core driver of fungal stress adaptation

Ping-Hung Hsieh, Yusuke Sasaki, Chu-I Yang, Zong‐Yen Wu, Andrei Stecca Steindorff, Sajeet Haridas, Jing Ke, Zia Fatma, Zhiying Zhao, Dana A. Opulente, Siwen Deng, Chris Todd Hittinger, Igor V. Grigoriev, Bruce S. Dien, Huimin Zhao, , Yasuo Yoshikuni

MAESTRO identifies tandem paralog copy number variation as a key mechanism for stress adaptation in Pichia kudriavzevii, linking it to drug resistance and environmental tolerance.

bioRxiv · Aug 29, 2025 · PreprintGenomics

A landing pad system for multicopy gene integration in Issatchenkia orientalis

Zia Fatma, Shih‐I Tan, Aashutosh Girish Boob, Huimin Zhao

This paper develops a landing pad system for efficient multicopy gene integration in Issatchenkia orientalis using CRISPR-Cas9, enabling the construction of complex metabolic pathways with high integration efficiency.

bioRxiv · May 21, 2023 · PreprintSynthetic Biology

An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis

Vinh Gia Tran, Somesh Mishra, Sarang S. Bhagwat, Saman Shafaei, Yihui Shen, Jayne L. Allen, Benjamin A. Crosly, Shih‐I Tan, Zia Fatma, Joshua D. Rabinowitz, Jeremy S. Guest, Vijay Singh, Huimin Zhao

This paper describes an end-to-end pipeline for cost-effective succinic acid production using Issatchenkia orientalis, achieving high titers and financial viability with reduced greenhouse gas emissions.

bioRxiv · Apr 30, 2023 · PreprintSynthetic Biology

Proteome capacity constraints favor respiratory ATP generation

Yihui Shen, Hoang V. Dinh, Edward R. Cruz, Catherine M. Call, Heide Baron, Rolf-Peter Ryseck, Jimmy Pratas, Arjuna M. Subramanian, Zia Fatma, Daniel Weilandt, Sudharsan Dwaraknath, Tianxia Xiao, John I. Hendry, Vinh Gia Tran, Lifeng Yang, , Joshua D. Rabinowitz

The paper shows mitochondrial respiration is more proteome-efficient than aerobic glycolysis in yeast and mammals, with flexibility arising from maintaining a fermentation-capable proteome.

bioRxiv · Aug 10, 2022 · PreprintSystems Biology