Zhiying Zhao

Active zone remodeling by Bruchpilot couples synaptic architecture to Kv1/Shaker excitability control

This study shows that Bruchpilot remodeling couples synaptic structure to Kv1/Shaker channel control of excitability, restoring function in sleepless mutants.

MAESTRO uncovers tandem paralog dynamics as a core driver of fungal stress adaptation

MAESTRO identifies tandem paralog copy number variation as a key mechanism for stress adaptation in Pichia kudriavzevii, linking it to drug resistance and environmental tolerance.

An active Unc13A is Reboundless in sleep homeostasis

This study shows that a constitutively active form of Unc13A reduces sleep rebound after deprivation, suggesting a role for SNARE complex dynamics in sleep homeostasis.

Cognitive hyperplasticity drives insomnia

The paper shows that insomniac Drosophila mutants exhibit enhanced memory and mushroom body overgrowth, which are modulated by PKA signaling, suggesting a link between cognitive hyperplasticity and sleep deficits.