RAB5c controls the assembly of non-canonical autophagy machinery to promote phagosome maturation and microbicidal function of macrophages
Edismauro Garcia Freitas Filho, Isabella Zaidan, Marlon Fortes-Rocha, Daniel Leonardo Alzamora-Terrel, Carolina Bifano, Patrícia Alves de Castro, Renan Eugênio Araujo Piraine, Camila Figueiredo Pinzan, Caroline Patini Rezende, Emilio Boada-Romero, Fausto Bruno dos Reis Almeida, Gustavo Henrique Goldman, Oliver Florey, Larissa D. Cunha
This study identifies RAB5c's role in regulating non-canonical autophagy machinery to enhance phagosome maturation and microbial killing by macrophages.
bioRxiv · Mar 25, 2025 · PreprintImmunology