Author

Chrystelle Perruchoud

University of GenevaORCID 0000-0002-2070-7623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:non-human primate· 1

Frequent Co-Authors

Brigitte GalliotiD· 4 shared Matthias Christian VoggiD· 3 shared Christine RamponiD· 2 shared Laura Iglesias OlléiD· 2 shared Leonardo L BeccariiD· 2 shared Paul Gerald Layague SancheziD· 2 shared Sophie VriziD· 2 shared Wanda Christa BuzgariuiD· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersDevelopmental Biology

Brigitte GalliotORCID

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4 papers

Recent·Most cited

Developmental BiologyBiomedicinesPeer-reviewedJun 8, 2024

The Wnt/β-catenin/TCF/Sp5/Zic4 gene network that regulates head organizer activity in Hydra is differentially regulated in epidermis and gastrodermis

Laura Iglesias Ollé, Chrystelle Perruchoud, Paul Gerald Layague Sanchez…·Brigitte Galliot

The paper investigates differential regulation of the Wnt/β-catenin/TCF/Sp5/Zic4 network in Hydra's epidermis and gastrodermis, revealing distinct roles in head organizer activity.

5 citations

experimental assay

Developmental BiologybioRxivPreprintDec 22, 2021

The transcription factor Zic4 acts as a transdifferentiation switch

Matthias Christian Vogg, Jaroslav Ferenc, Wanda Christa Buzgariu…·Charisios D. Tsiairis

The paper shows Zic4 silencing induces transdifferentiation in Hydra and identifies a Wnt-controlled GRN that regulates cell fate and cell cycle re-entry.

DOI 10.1101/2021.12.22.473838

non-human primatestatistical model

Developmental BiologybioRxivPreprintMar 24, 2019

Generic and context-dependent gene modulations during Hydra whole body regeneration

Yvan Wenger, Wanda Christa Buzgariu, Chrystelle Perruchoud…·Brigitte Galliot

The paper compares apical and basal regeneration in Hydra, identifying gene modulations and signaling pathways involved in regeneration.

38 citations

bulk RNA-seqstatistical model

Developmental BiologyNature CommunicationsPeer-reviewedJan 14, 2019

An evolutionary-conserved Wnt3/β-catenin/Sp5 feedback loop restricts head organizer activity in Hydra

Matthias Christian Vogg, Leonardo L Beccari, Laura Iglesias Ollé…·Brigitte Galliot

The paper identifies Sp5 as a novel inhibitor of the Wnt/β-catenin signaling pathway in Hydra, revealing an evolutionary-conserved feedback loop that restricts head organizer activity.

131 citationstop 1%

bulk RNA-seqstatistical model