Paul Gerald Layague Sanchez

This study compares body shapes and histology across goldfish strains to show that similar globular shapes arise through different developmental pathways.

The paper investigates differential regulation of the Wnt/β-catenin/TCF/Sp5/Zic4 network in Hydra's epidermis and gastrodermis, revealing distinct roles in head organizer activity.

The paper examines muscle fiber distribution in twin-tail goldfish and finds similar patterns in related species, suggesting shared developmental mechanisms despite morphological differences.

This study shows glycolysis regulates the segmentation clock period in mouse embryos through a glycolysis-FBP-Wnt signaling axis, with FBP entraining Wnt oscillations.

The paper investigates rhythmic yolk contractions in goldfish eggs, finding they are intrinsic, independent of fertilization, and may influence dorsoventral patterning.

The paper uses a coarse-grained theoretical-experimental approach to study the dynamics of the mouse embryonic segmentation clock, revealing its non-linear oscillator characteristics and long-term feedbacks.

The paper shows Zic4 silencing induces transdifferentiation in Hydra and identifies a Wnt-controlled GRN that regulates cell fate and cell cycle re-entry.