Author

Kuei Ching Hsiung

University College LondonORCID 0000-0002-2107-6368Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2

Frequent Co-Authors

David GemsiD· 2 shared Hannah ChapmaniD· 2 shared Xiaoya WeiiD· 2 shared Aihan ZhangiD· 1 shared Bruce ZhangiD· 1 shared Chiminh Nguyen Hong· 1 shared Collin Y. EwaldiD· 1 shared Isadora RawlinsoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetics

David GemsORCID

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2 papers

Recent·Most cited

Strong inhibition of insulin/IGF-1 signaling in early-mid adulthood compresses morbidity, but in later life accelerates aging

Bruce Zhang, Kuei Ching Hsiung, Reva Biju, Marybelle Cameron-Pack, Xiaoya Wei, Hannah Chapman, Melisa Kelaj, Aihan Zhang, Chiminh Nguyen Hong, Collin Y. Ewald, David Gems

This study shows that reducing insulin/IGF-1 signaling in early adulthood extends healthspan and lifespan, but in later life, it accelerates aging and reduces lifespan.

bioRxiv · Apr 16, 2026 · PreprintGenetics

Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

Kuei Ching Hsiung, Hannah Chapman, Xiaoya Wei, Xiaoyu Sun, Isadora Rawlinson, David Gems

This study shows that autophagy gene knockdown in C. elegans affects lifespan in a highly condition-dependent manner, with variable outcomes based on genetic background, temperature, and experimental conditions.

bioRxiv · Jul 28, 2025 · PreprintGenetics