Isadora Rawlinson

This study uses mouse models with tau mutations to show two distinct pathogenic mechanisms in tauopathies, with different progression patterns and responses to amyloid.

This study shows that autophagy gene knockdown in C. elegans affects lifespan in a highly condition-dependent manner, with variable outcomes based on genetic background, temperature, and experimental conditions.

The paper identifies tau filaments within extracellular vesicles from Alzheimer's disease patients using mass spectrometry and cryo-electron microscopy.