Elizabeth S. Egan

This study uses a CRISPR screen to identify genes critical for erythroblast enucleation, finding CLIC3 and VAMP8 as key factors with distinct roles in the process.

This study identifies CD44 as a host factor promoting Plasmodium falciparum invasion through cross-linking, which alters RBC membrane structure and enhances ligand-receptor interactions.

This study identifies NUAK1 as a critical host factor for Plasmodium falciparum infection and shows that NUAK1 inhibitors block parasite growth.

The study evaluates alternative IMDM products for ex-vivo erythropoiesis and finds FG0465 supports maximal erythroid cell proliferation and enucleation.

The paper identifies extrachromosomal DNA enriched with var genes in Plasmodium falciparum, suggesting a mechanism for rapid antigenic diversification.

The paper investigates how common host red blood cell variation affects Plasmodium falciparum parasite growth in healthy humans, finding that non-pathogenic polymorphisms in RBC proteins significantly explain parasite fitness variation.