Tissue-Specific Prevalence and Clonal Architecture of BRCA1/2 LOH-Inducing Chromosomal Aneuploidy
Xinfeng Wang, Saumya Dushyant Sisoudiya, Mahad Bihie…·Kuan‐lin Huang
The paper investigates tissue-specific chromosomal deletions in BRCA1/2-related cancers using bulk and single-cell data, finding early deletions of 17q and 13q in breast and ovarian cancers.