Saumya Dushyant Sisoudiya

The paper identifies increased GPCR pathway activity in breast cancer ovarian metastases and links it to migration and F-actin reorganization through CaSR.

The paper identifies reversion mutations in homologous recombination genes across cancers, showing they restore DNA repair and confer PARP inhibitor resistance through specific structural alterations.

The paper investigates tissue-specific chromosomal deletions in BRCA1/2-related cancers using bulk and single-cell data, finding early deletions of 17q and 13q in breast and ovarian cancers.

The paper investigates functional differences between EML4-ALK variants V1 and V3 in lung cancer using mouse models and human data, showing variant-specific effects on tumorigenesis.