The paper presents a genetic resource of 15,684 individuals of African ancestry, demonstrating its utility in replicating and discovering disease associations.

Genetics in Medicine · Mar 1, 2026Peer-reviewedGenetic & Genomic Medicine

Epstein-Barr virus nuclear antigen 2 (EBNA2) extensively rewires the human chromatin landscape at autoimmune risk loci

Ted Hong, Sreeja Parameswaran, Omer A. Donmez, Daniel Miller, Carmy R. Forney, Michael Lape, Mariana Saint Just Ribeiro, Jun Liang, Lee Edsall, Albert Frank Magnusen, William E. Miller, Iouri Chepelev, John B. Harley, Bo Zhao, Leah Claire Kottyan, Matthew T. Weirauch

This study shows EBNA2 alters chromatin structure and gene expression at autoimmune risk loci, linking viral infection to genetic risk mechanisms in autoimmune diseases.

Genome Research · Dec 1, 2021Peer-reviewedGenomics

Genomic features of BRDT binding sites in gene units suggest transcriptional partners and specific epigenetic landscapes to regulate transcriptional activity during spermatogenesis

Yoon Ra Her, Li Wang, Iouri Chepelev, Marcia Manterola, Binyamin D. Berkovits, Kairong Cui, Keji Zhao, Debra J. Wolgemuth

The paper identifies BRDT binding sites in gene units during spermatogenesis and links them to specific transcription factors and epigenetic features that regulate gene expression.

Molecular Reproduction and Development · Jan 20, 2021Peer-reviewedDevelopmental Biology