Author

Janani Ramesh

Harvard UniversityORCID 0000-0002-2137-500XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Abdul Jalil RufaihahiD· 1 shared Alfredo Franco‐ObregóniD· 1 shared Anna ShcherbinaiD· 1 shared Bing Shao ChiaiD· 1 shared Binny Priya Sesurajan· 1 shared Brianna E. HeathiD· 1 shared Choong Tat KengiD· 1 shared Christine Wu NordahliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Abdul Jalil RufaihahORCID

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2 papers

Recent·Most cited

Modeling Adeno-Associated Viral Vector 6-mediated In Vivo Gene Delivery to Expanded Non-Mobilized Haemopoietic Stem Cells from Transfusion dependent Thalassemia Patients in a Humanized Mouse

Janani Ramesh, Karthikeyan Kandasamy, Nur Nazneen Binte Yusof, I. Sujuandy, Choong Tat Keng, Liwei Chen, Bing Shao Chia, Min Liu, Zhisheng Her, Marek Kukumberg, Kian Chuan Sia, Siti Humairah Mohd Rodhi, Zhen Ying Fu, Abdul Jalil Rufaihah, Alfredo Franco‐Obregón, , Citra Nurfarah Zaini Mattar

This study demonstrates the feasibility of using dual-ssAAV6 vectors for in vivo gene delivery to HSC from thalassemia patients in a humanized mouse model, showing efficient transduction and long-term persistence.

bioRxiv · Jun 17, 2025 · PreprintMolecular Biology

Cellular mechanisms of early brain overgrowth in autistic children: elevated levels of GPX4 and resistance to ferroptosis

Siwei Chen, Anna Shcherbina, Simon T. Schafer, Zoe A. Mattingly, Janani Ramesh, Cyndhavi Narayanan, Sravani Banerjee, Brianna E. Heath, Melissa Regester, Ivette Chen, Sudhir Thakurela, Joachim Franz Hallmayer, Ruth M. O'Hara, Marjorie Solomon, Christine Wu Nordahl, , Sundari Chetty

The paper investigates cellular mechanisms of brain overgrowth in autistic children with megalencephaly, finding elevated GPX4 and resistance to ferroptosis in neural progenitor cells.

bioRxiv · Jan 30, 2025 · PreprintNeuroscience