Author

Ayman Al Haj Zen

British Heart FoundationORCID 0000-0002-2145-2925Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Carlos Pulido-QuetglasiD· 1 shared Frank SchmidtiD· 1 shared Heba SailemiD· 1 shared Khalid OuararhniiD· 1 shared Lütfiye Yıldız ÖzeriD· 1 shared Michela CoaniD· 1 shared Nehad M. AlajeziD· 1 shared Radhakrishnan Vishnubalaji· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Carlos Pulido-QuetglasORCID

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2 papers

Recent·Most cited

Robust CRISPR Screens Identify TPL1 as a Novel Long Noncoding RNA Driving Triple-Negative Breast Cancer Hallmarks

Ramesh Elango, Sunandini Ramnarayanan, Radhakrishnan Vishnubalaji, Lütfiye Yıldız Özer, Michela Coan, Yifan Yu, Sunkyu Choi, Tina Uroda, Carlos Pulido-Quetglas, Frank Schmidt, Khalid Ouararhni, Ayman Al Haj Zen, Rory Johnson, Nehad M. Alajez

The paper identifies TPL1 as a novel long noncoding RNA that drives triple-negative breast cancer hallmarks through multiple molecular mechanisms.

bioRxiv · Aug 6, 2025 · PreprintCancer Biology

Multi-Parametric Profiling of Endothelial Cell Networks Reveals Functional Role of Glutamate Receptors in Angiogenesis

Heba Sailem, Ayman Al Haj Zen

The paper develops a high-content analysis framework to quantify endothelial network morphology and identifies glutamate receptor-targeting drugs that enhance branching and connectivity in angiogenesis.

Scientific Reports · Aug 14, 2020Peer-reviewedSystems Biology