Author

Khalid Ouararhni

Centre National de la Recherche ScientifiqueORCID 0000-0002-1245-3758Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Ali HamicheiD· 2 shared Adèle MangelinckiD· 1 shared Ayman Al Haj ZeniD· 1 shared Bruno P. KlaholziD· 1 shared C. Ruebe· 1 shared Carl ManniD· 1 shared Carlos Pulido-QuetglasiD· 1 shared Céline Derbois· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersGenetics

Ali HamicheORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Robust CRISPR Screens Identify TPL1 as a Novel Long Noncoding RNA Driving Triple-Negative Breast Cancer Hallmarks

Ramesh Elango, Sunandini Ramnarayanan, Radhakrishnan Vishnubalaji, Lütfiye Yıldız Özer, Michela Coan, Yifan Yu, Sunkyu Choi, Tina Uroda, Carlos Pulido-Quetglas, Frank Schmidt, Khalid Ouararhni, Ayman Al Haj Zen, Rory Johnson, Nehad M. Alajez

The paper identifies TPL1 as a novel long noncoding RNA that drives triple-negative breast cancer hallmarks through multiple molecular mechanisms.

bioRxiv · Aug 6, 2025 · PreprintCancer Biology

The H2A.J histone variant contributes to Interferon-Stimulated Gene expression in senescence by its weak interaction with H1 and the derepression of repeated DNA sequences

Adèle Mangelinck, Clément Coudereau, Régis Courbeyrette, Khalid Ouararhni, Ali Hamiche, Christophe E. Redon, William M. Bonner, Erwin van Dijk, Céline Derbois, Robert Olaso, Jean‐François Deleuze, François Fenaille, C. Ruebe, Jean‐Yves Thuret, Carl Mann

This study identifies H2A.J's role in promoting ISG expression during senescence through its interaction with H1 and derepression of repeated DNA sequences.

bioRxiv · Oct 29, 2020 · PreprintGenetics

3D clustering analysis of super-resolution microscopy data by 3D Voronoi tessellations

Leonid P. Andronov, Jonathan Michalon, Khalid Ouararhni, Igor M. Orlov, Ali Hamiche, Jean‐Luc Vonesch, Bruno P. Klaholz

The paper introduces 3DClusterViSu, a method for analyzing 3D SMLM data using Voronoi tessellations, demonstrating its effectiveness on microtubules and histone proteins.

Bioinformatics · Apr 2, 2018Peer-reviewedBioinformatics