Ashley Perkins Barry

The paper assesses EBV dependence in various infected cell models and finds that EBV loss sensitivity varies across cell types, with lymphoid malignancies being more dependent than gastric adenocarcinoma lines.

This study uses spatial transcriptomics to show that EBV+ HIV-associated NHLs have distinct tumor microenvironment features, including immunosuppressive pathways and spatial organization similar to lymphoid tissues.

This study uses single-cell RNA sequencing to analyze the effects of HDAC inhibitors on EBV lytic reactivation in B lymphoblasts, identifying abortive and refractory states.

This study identifies fatty acid desaturases SCD1 and FADS2 as critical for EBV-induced B cell proliferation and reveals their role in promoting metabolic pathways that support lymphoma growth.