Synthetic BiologyACS SensorsPeer-reviewed
Rapid Isothermal Detection of Heavy Metals via Transcription-Factor-Gated DNA Strand Synthesis
Padric M. Garden, Alexander A. Green
This paper introduces TONE, a rapid, isothermal biosensing platform for heavy metal detection using transcription-factor-gated DNA strand-displacement amplification, achieving low detection limits for copper and lead.
DOI 10.1021/acssensors.6c02342