Ji Chen

Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci

This paper combines multi-trait fine-mapping and functional annotation to improve the identification of causal variants at glycaemic trait loci, reducing the number of likely causal variants significantly.

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

This study identifies 242 genetic loci for glycaemic traits using trans-ancestry meta-analysis, finding 99 novel loci and improved fine-mapping resolution compared to single-ancestry analyses.

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

The paper identifies genetic variants and transcripts associated with glycemic traits by analyzing exome-array data from 144,600 individuals, highlighting tissue-specific roles in glucose regulation.