SCAF1 driven polyadenylation site usage regulates mRNA isoform expression and neuronal differentiation
Smaragda Kompocholi, Nikolaos Stamidis, Haiyue Liu, Gertrud M. Hjortø, Eleni Kafkia, Sarah F. Ruidiaz, Thomas C. R. Miller, Jan Jakub Żylicz, Lea H. Gregersen
This study shows that SCAF1 regulates polyadenylation site usage, affecting mRNA isoform expression and neuronal differentiation in mouse embryonic stem cells.
bioRxiv · Dec 10, 2025 · PreprintMolecular Biology