Author

Jeroen Roelofs

The University of Kansas Health SystemORCID 0000-0003-0944-2465Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:yeast· 1

Frequent Co-Authors

Bret FreudenthaliD· 1 shared Carlos A. CastañedaiD· 1 shared Daniel Adam KrautiD· 1 shared Emily A. DanieliD· 1 shared Erin Mulvey· 1 shared Jessica K. NibloiD· 1 shared Kylie J. WaltersiD· 1 shared Mandeep Kaur· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Bret FreudenthalORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedSep 21, 2026

Structure of Blm10:13S proteasome intermediate reveals parallel assembly pathways for the proteasome core particle

Mandeep Kaur, Xiang Chen, Stella Y. Lee…·Jeroen Roelofs

The paper presents cryo-EM structures of a Blm10:13S proteasome intermediate, revealing parallel assembly pathways for the proteasome core particle involving Blm10 and Pba1/Pba2.

5 citationstop 3%

cryo-EMexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintMar 14, 2025

STI1 domain dynamically engages transient helices in disordered regions to drive self-association and phase separation of yeast ubiquilin Dsk2

Nirbhik Acharya, Emily A. Daniel, Thuy Phuong Dao…·Carlos A. Castañeda

This study identifies the STI1 domain's role in driving Dsk2 self-association and phase separation through interactions with transient helices in disordered regions, with implications for proteasome condensate formation.

3 citations

yeastprotein structure

𝕏 PostBluesky