Author

Matthew G. Lackemeyer

National Institutes of HealthORCID 0000-0002-2174-9630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Brett EatoniD· 2 shared Abel D. Ordonez· 1 shared Amy L Cregger· 1 shared C. Paul MorrisiD· 1 shared Chase A Gonzales· 1 shared Christy N Raney· 1 shared Deborah S Gohegan· 1 shared Elena N. PostnikovaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Brett EatonORCID

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Author profile →

2 papers

Recent·Most cited

Monkeypox Virus Clade IIb Isolate Exhibits Reduced Virulence Relative to Clade IIa Isolates in Multiple Murine Models

Stephanie V. Trefry, Santiago Vidal-Freire, Mayanka Awasthi, Abel D. Ordonez, Brett Eaton, Randy J. Hart, Christy N Raney, Amy L Cregger, Chase A Gonzales, Robert N Enamorado, Nelson A Martinez, Deborah S Gohegan, Matthew G. Lackemeyer, Tinoush Moulaei, N.E. Ziolkowska, , Farooq Nasar

This study compares the virulence of MPXV clade IIa and IIb isolates in multiple murine models, finding IIb is significantly less virulent with lower lethality.

Journal of Virology · Jul 15, 2026Peer-reviewedMicrobiology

High-throughput virus quantification using cytopathic effect area analysis by deep learning

Michael J. Murphy, Steven Mazur, Elena N. Postnikova, Brett Eaton, Gregory A. Kocher, Winston T. Chu, Matthew G. Lackemeyer, Syed Qasim Gilani, Jens H. Kuhn, Michael R. Holbrook, C. Paul Morris

This paper develops a deep learning-based method to quantify infectious viruses using cytopathic effect area analysis, improving throughput and reducing manual bias.

bioRxiv · Sep 11, 2025 · PreprintMicrobiology