Author

Carlos Saúl Rodríguez-Roque

University Hospital BonnORCID 0000-0002-2176-1066Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Annalena LieseniD· 1 shared Hubert SchorleiD· 1 shared Katrin PaeschkeiD· 1 shared Rashidul IslamiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Annalena LiesenORCID

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1 paper

Recent·Most cited

G-quadruplex targeting by CX-5461 as a novel therapeutic strategy in testicular germ cell tumors

Rashidul Islam, Annalena Liesen, Carlos Saúl Rodríguez-Roque, Katrin Paeschke, Hubert Schorle

This study evaluates G4-ligands in TGCTs, finding CX-5461 induces p53-dependent cell death by stabilizing G4s and disrupting RNA polymerase I transcription.

bioRxiv · Sep 9, 2026 · PreprintCancer Biology