Extended culture of 2D gastruloids to model human mesoderm development
Bohan Chen, Hina Khan, Zhiyuan Yu, LiAng Yao, Emily Freeburne, Kyoung Jo, Craig N. Johnson, Idse Heemskerk
The paper extends the culture of 2D gastruloids to 96h, revealing a phase of mesoderm differentiation with spatial organization similar to embryos.
Nature Methods · May 7, 2025Peer-reviewedDevelopmental Biology