Inhibition of DKK-1 by WAY262611 Inhibits Osteosarcoma Metastasis
Adit L. Tal, Shimara Gunawardana-Zeigler, Da Peng, Yuqi Tan, Natalia Muñoz Perez, Rachel Offenbacher, Laurel Kastner, Paul Ciero, Matthew E. Randolph, Yun Gong, Hong‐Wen Deng, Patrick Cahan, David Mark Loeb
This study shows that the small molecule inhibitor WAY262611 inhibits osteosarcoma metastasis by activating Wnt signaling and inducing osteoblastic differentiation.
Molecular Cancer Therapeutics · Jan 9, 2025Peer-reviewedCancer Biology